Thrombotic Thrombocytopenic Purpura due to Checkpoint Inhibitors

Ipilimumab is a monoclonal antibody that enhances the efficacy of the immune system by targeting a cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), which is a protein receptor that downregulates the immune system. Nivolumab is also a humanized monoclonal antibody that targets another protein re...

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Bibliographic Details
Main Authors: Alexey Youssef, Nawara Kasso, Antonio Sergio Torloni, Michael Stanek, Tomislav Dragovich, Mark Gimbel, Fade Mahmoud
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2018/2464619