Optimization of the All-D Peptide D3 for Aβ Oligomer Elimination.
The aggregation of amyloid-β (Aβ) is postulated to be the crucial event in Alzheimer's disease (AD). In particular, small neurotoxic Aβ oligomers are considered to be responsible for the development and progression of AD. Therefore, elimination of thesis oligomers represents a potential causal...
Main Authors: | Antonia Nicole Klein, Tamar Ziehm, Markus Tusche, Johan Buitenhuis, Dirk Bartnik, Annett Boeddrich, Thomas Wiglenda, Erich Wanker, Susanne Aileen Funke, Oleksandr Brener, Lothar Gremer, Janine Kutzsche, Dieter Willbold |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4841555?pdf=render |
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