Mucopolysaccharidosis IIIB, a lysosomal storage disease, triggers a pathogenic CNS autoimmune response

<p>Abstract</p> <p>Background</p> <p>Recently, using a mouse model of mucopolysaccharidosis (MPS) IIIB, a lysosomal storage disease with severe neurological deterioration, we showed that MPS IIIB neuropathology is accompanied by a robust neuroinflammatory response of un...

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Bibliographic Details
Main Authors: Popovich Phillip G, Divers Erin, DiRosario Julianne, Killedar Smruti, McCarty Douglas M, Fu Haiyan
Format: Article
Language:English
Published: BMC 2010-07-01
Series:Journal of Neuroinflammation
Online Access:http://www.jneuroinflammation.com/content/7/1/39