TGF-β1 stimulates epithelial–mesenchymal transition and cancer-associated myoepithelial cell during the progression from in situ to invasive breast cancer

TGF-β1 stimulates epithelial–mesenchymal transition and cancer-associated myoepithelial cell during the progression from in situ to invasive breast cancer

Abstract Background The progression of ductal carcinoma in situ (DCIS) into invasive ductal carcinoma (IDC) is prevented by normal breast myoepithelial cells. Studies have suggested that EMT-associated genes were enriched in IDC in contrast to DCIS. This paper explored the relationship and potential...

Full description

Bibliographic Details
Main Authors: Li Wang, Cong Xu, Xia Liu, Yang Yang, Lu Cao, Guomin Xiang, Fang Liu, Shuling Wang, Jing Liu, Qingxiang Meng, Jiao Jiao, Yun Niu
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Cancer Cell International
Subjects:
DCIS
Progression
Epithelial–mesenchymal transition
Myoepithelial cell
TGF-β1
Online Access:https://doi.org/10.1186/s12935-019-1068-7

Internet

https://doi.org/10.1186/s12935-019-1068-7

Similar Items