Morphological and pathological evolution of the brain microcirculation in aging and Alzheimer's disease.

Key pathological hallmarks of Alzheimer's disease (AD), including amyloid plaques, cerebral amyloid angiopathy (CAA) and neurofibrillary tangles do not completely account for cognitive impairment, therefore other factors such as cardiovascular and cerebrovascular pathologies, may contribute to...

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Bibliographic Details
Main Authors: Jesse M Hunter, Jason Kwan, Michael Malek-Ahmadi, Chera L Maarouf, Tyler A Kokjohn, Christine Belden, Marwan N Sabbagh, Thomas G Beach, Alex E Roher
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3353981?pdf=render