The Protective Effects of Pre- and Post-Administration of Micronized Palmitoylethanolamide Formulation on Postoperative Pain in Rats

Background: Postoperative pain (PO) is a common form of acute pain. Inadequate PO treatment is an important health problem, as it leads to worse outcomes, such as chronic post-surgical pain. Therefore, it is necessary to acquire new knowledge on PO mechanisms to develop therapeutic options with grea...

Full description

Bibliographic Details
Main Authors: Rosalba Siracusa, Roberta Fusco, Marika Cordaro, Alessio F. Peritore, Ramona D’Amico, Enrico Gugliandolo, Rosalia Crupi, Tiziana Genovese, Maurizio Evangelista, Rosanna Di Paola, Salvatore Cuzzocrea, Daniela Impellizzeri
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/21/20/7700