Significant Effects of Oral Phenylbutyrate and Vitamin D3 Adjunctive Therapy in Pulmonary Tuberculosis: A Randomized Controlled Trial.

Development of new tuberculosis (TB) drugs and alternative treatment strategies are urgently required to control the global spread of TB. Previous results have shown that vitamin D3 (vitD3) and 4-phenyl butyrate (PBA) are potent inducers of the host defense peptide LL-37 that possess anti-mycobacter...

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Main Authors: Akhirunnesa Mily, Rokeya Sultana Rekha, S M Mostafa Kamal, Abu Saleh Mohammad Arifuzzaman, Zeaur Rahim, Lamia Khan, Md Ahsanul Haq, Khaliqu Zaman, Peter Bergman, Susanna Brighenti, Gudmundur H Gudmundsson, Birgitta Agerberth, Rubhana Raqib
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4578887?pdf=render