Investigating multiple candidate genes and nutrients in the folate metabolism pathway to detect genetic and nutritional risk factors for lung cancer.

Investigating multiple candidate genes and nutrients in the folate metabolism pathway to detect genetic and nutritional risk factors for lung cancer.

Folate metabolism, with its importance to DNA repair, provides a promising region for genetic investigation of lung cancer risk. This project investigates genes (MTHFR, MTR, MTRR, CBS, SHMT1, TYMS), folate metabolism related nutrients (B vitamins, methionine, choline, and betaine) and their gene-nut...

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Bibliographic Details
Main Authors: Michael D Swartz, Christine B Peterson, Philip J Lupo, Xifeng Wu, Michele R Forman, Margaret R Spitz, Ladia M Hernandez, Marina Vannucci, Sanjay Shete
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3553105?pdf=render

Internet

http://europepmc.org/articles/PMC3553105?pdf=render

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