%0 Article %A Alexander V. Aksenov %I MDPI AG %D 2021 %G English %B Molecules %@ 1420-3049 %T Electrophilically Activated Nitroalkanes in Synthesis of 3,4-Dihydroquinozalines %U https://www.mdpi.com/1420-3049/26/14/4274 %X Nitroalkanes activated with polyphosphoric acid serve as efficient electrophiles in reactions with various nucleophilic amines. Strategically placed second functionality allows for the design of annulation reactions enabling preparation of various heterocycles. This strategy was employed to develop an innovative synthetic approach towards 3,4-dihydroquinazolines from readily available 2-(aminomethyl)anilines.