Axitinib in combination with radiotherapy for advanced hepatocellular carcinoma: a phase I clinical trial

Abstract Background To investigate maximum tolerated dose (MTD) of axitinib, a selective vascular endothelial growth factor receptor 1–3 inhibitor, in combination with radiotherapy (RT) for advanced hepatocellular carcinoma (HCC). Methods This phase I study followed the rule of traditional 3 + 3 des...

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Bibliographic Details
Main Authors: Kai-Lin Yang, Mau-Shin Chi, Hui-Ling Ko, Yi-Ying Huang, Su-Chen Huang, Yu-Min Lin, Kwan-Hwa Chi
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Radiation Oncology
Subjects:
Online Access:https://doi.org/10.1186/s13014-020-01742-w