AAV vector distribution in the mouse respiratory tract following four different methods of administration

AAV vector distribution in the mouse respiratory tract following four different methods of administration

Abstract Background Targeted delivery of gene therapy vectors to the mouse respiratory tract is often performed via intranasal or intratracheal administration; however, there can be a great deal of variability between these methods, which could potentially influence experimental results. Improving t...

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Bibliographic Details
Main Authors: Lisa A. Santry, Joelle C. Ingrao, Darrick L. Yu, Jondavid G. de Jong, Laura P. van Lieshout, Geoffrey A. Wood, Sarah K. Wootton
Format: Article
Language:English
Published: BMC 2017-05-01
Series:BMC Biotechnology
Subjects:
Adeno-associated virus
Vector instillation
Transgene expression
Intratracheal
Intranasal
Intubation
Online Access:http://link.springer.com/article/10.1186/s12896-017-0365-2

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http://link.springer.com/article/10.1186/s12896-017-0365-2

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