Endoplasmic Reticulum Stress, Unfolded Protein Response, and Cancer Cell Fate

Perturbation of endoplasmic reticulum (ER) homeostasis results in a stress condition termed “ER stress” determining the activation of a finely regulated program defined as unfolded protein response (UPR) and whose primary aim is to restore this organelle’s physiological activity. Several physiologic...

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Bibliographic Details
Main Authors: Marco Corazzari, Mauro Piacentini, Mara Gagliardi, Gian Maria Fimia
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Oncology
Subjects:
E2F
Online Access:http://journal.frontiersin.org/article/10.3389/fonc.2017.00078/full