A Joint Less Ordinary: Intriguing Roles for Hedgehog Signalling in the Development of the Temporomandibular Synovial Joint

This review highlights the essential role of Hedgehog (Hh) signalling in the developmental steps of temporomandibular joint (TMJ) formation. We review evidence for intra- and potentially inter-tissue Hh signaling as well as Glioma-Associated Oncogene Homolog (GLI) dependent and independent functions...

Full description

Bibliographic Details
Main Authors: Malgorzata Kubiak, Mark Ditzel
Format: Article
Language:English
Published: MDPI AG 2016-08-01
Series:Journal of Developmental Biology
Subjects:
Hh
IHH
GLI
Online Access:http://www.mdpi.com/2221-3759/4/3/25