Immunogenicity and Efficacy of a Novel Multi-Antigenic Peptide Vaccine Based on Cross-Reactivity between Feline and Human Immunodeficiency Viruses

Immunogenicity and Efficacy of a Novel Multi-Antigenic Peptide Vaccine Based on Cross-Reactivity between Feline and Human Immunodeficiency Viruses

For the development of an effective HIV-1 vaccine, evolutionarily conserved epitopes between feline and human immunodeficiency viruses (FIV and HIV-1) were determined by analyzing overlapping peptides from retroviral genomes that induced both anti-FIV/HIV T cell-immunity in the peripheral blood mono...

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Bibliographic Details
Main Authors: Bikash Sahay, Alek M. Aranyos, Meerambika Mishra, Andrew C. McAvoy, Marcus M. Martin, Riuyu Pu, Sayaka Shiomitsu, Keijiro Shiomitsu, Michael J. Dark, Missa P. Sanou, Shannon R. Roff, Mobeen H. Rathore, Janet K. Yamamoto
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Viruses
Subjects:
FIV vaccine
HIV-1
T cell epitopes
cytotoxic T lymphocyte
polyfunctional T cells
Online Access:https://www.mdpi.com/1999-4915/11/2/136

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https://www.mdpi.com/1999-4915/11/2/136

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