Differential Role for Activating FcγRIII in Neointima Formation After Arterial Injury and Diet-Induced Chronic Atherosclerosis in Apolipoprotein E-Deficient Mice

Differential Role for Activating FcγRIII in Neointima Formation After Arterial Injury and Diet-Induced Chronic Atherosclerosis in Apolipoprotein E-Deficient Mice

Atherogenesis and arterial remodeling following mechanical injury are driven by inflammation and mononuclear cell infiltration. The binding of immune complexes (ICs) to immunoglobulin (Ig)-Fc gamma receptors (FcγRs) on most innate and adaptive immune cells induces a variety of inflammatory responses...

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Bibliographic Details
Main Authors: Yaw Asare, Janine Koehncke, Jaco Selle, Sakine Simsekyilmaz, Joachim Jankowski, Gansuvd Shagdarsuren, Johannes E. Gessner, Jürgen Bernhagen, Erdenechimeg Shagdarsuren
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Physiology
Subjects:
Fc gamma receptors
atherosclerosis
inflammation
neointima formation
hyperlipidemia
cytokine
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00673/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2020.00673/full

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