The anti-proliferative effect of L-carnosine correlates with a decreased expression of hypoxia inducible factor 1 alpha in human colon cancer cells.

The anti-proliferative effect of L-carnosine correlates with a decreased expression of hypoxia inducible factor 1 alpha in human colon cancer cells.

In recent years considerable attention has been given to the use of natural substances as anticancer drugs. The natural antioxidant dipeptide L-carnosine belongs to this class of molecules because it has been proved to have a significant anticancer activity both in vitro and in vivo. Previous studie...

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Main Authors: Barbara Iovine, Giorgia Oliviero, Mariangela Garofalo, Maria Orefice, Francesca Nocella, Nicola Borbone, Vincenzo Piccialli, Roberto Centore, Massimiliano Mazzone, Gennaro Piccialli, Maria Assunta Bevilacqua
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4013086?pdf=render

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http://europepmc.org/articles/PMC4013086?pdf=render

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