Concentrated Conditioned Media from Adipose Tissue Derived Mesenchymal Stem Cells Mitigates Visual Deficits and Retinal Inflammation Following Mild Traumatic Brain Injury

Concentrated Conditioned Media from Adipose Tissue Derived Mesenchymal Stem Cells Mitigates Visual Deficits and Retinal Inflammation Following Mild Traumatic Brain Injury

Blast concussions are a common injury sustained in military combat today. Inflammation due to microglial polarization can drive the development of visual defects following blast injuries. In this study, we assessed whether anti-inflammatory factors released by the mesenchymal stem cells derived from...

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Bibliographic Details
Main Authors: Kumar Abhiram Jha, Mickey Pentecost, Raji Lenin, Lada Klaic, Sally L. Elshaer, Jordy Gentry, John M. Russell, Alex Beland, Anton Reiner, Veronique Jotterand, Nicolas Sohl, Rajashekhar Gangaraju
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:International Journal of Molecular Sciences
Subjects:
TBI
adult stem cells
TSG6
retinal ganglion cells
oxidative stress
TIMP1
microglia
trans-endothelial electrical resistance
Online Access:http://www.mdpi.com/1422-0067/19/7/2016

Internet

http://www.mdpi.com/1422-0067/19/7/2016

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