Unfolded Protein Response and Crohn’s Diseases: A Molecular Mechanism of Wound Healing in the Gut

Endoplasmic reticulum (ER) stress triggers a series of signaling and transcriptional events termed the unfolded protein response (UPR). Severe ER stress is associated with the development of fibrosis in different organs, including lung, liver, kidney, heart, and intestine. ER stress is an essential...

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Bibliographic Details
Main Author: Chao Li
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Gastrointestinal Disorders
Subjects:
Online Access:https://www.mdpi.com/2624-5647/3/1/4