Unfolded Protein Response and Crohn’s Diseases: A Molecular Mechanism of Wound Healing in the Gut
Endoplasmic reticulum (ER) stress triggers a series of signaling and transcriptional events termed the unfolded protein response (UPR). Severe ER stress is associated with the development of fibrosis in different organs, including lung, liver, kidney, heart, and intestine. ER stress is an essential...
Main Author: | |
---|---|
Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-02-01
|
Series: | Gastrointestinal Disorders |
Subjects: | |
Online Access: | https://www.mdpi.com/2624-5647/3/1/4 |