Prime-boost strategies in mucosal immunization affect local IgA production and the type of Th response

Prime-boost strategies in mucosal immunization affect local IgA production and the type of Th response

Combinations of different delivery routes for priming and boosting represent vaccination strategies that can modulate magnitude, quality, and localization of the immune response. A murine model was used to study T cell clonal expansion following nasal or subcutaneous priming, and secondary immune re...

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Bibliographic Details
Main Authors: Fabio eFiorino, Elena ePettini, Gianni ePozzi, Donata eMedaglini, Annalisa eCiabattini
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Immunology
Subjects:
Cytokines
T-cell priming
Prime-boost
nasal immunization
subcutaneous immunization
mucosal immune response
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00128/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00128/full

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