RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins.

RanBP2/Nup358 potentiates the translation of a subset of mRNAs encoding secretory proteins.

In higher eukaryotes, most mRNAs that encode secreted or membrane-bound proteins contain elements that promote an alternative mRNA nuclear export (ALREX) pathway. Here we report that ALREX-promoting elements also potentiate translation in the presence of upstream nuclear factors. These RNA elements...

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Bibliographic Details
Main Authors: Kohila Mahadevan, Hui Zhang, Abdalla Akef, Xianying A Cui, Serge Gueroussov, Can Cenik, Frederick P Roth, Alexander F Palazzo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23630457/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23630457/?tool=EBI

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