Ginsenoside Rg3 and Korean Red Ginseng extract epigenetically regulate the tumor-related long noncoding RNAs RFX3-AS1 and STXBP5-AS1

Ginsenoside Rg3 and Korean Red Ginseng extract epigenetically regulate the tumor-related long noncoding RNAs RFX3-AS1 and STXBP5-AS1

Background: Ginsenoside Rg3, a derivative of steroidal saponins abundant in ginseng, has a range of effects on cancer cells, including anti-cell proliferation and anti-inflammation activity. Here, we investigate two long noncoding RNAs (lncRNAs), STXBP5-AS1 and RFX3-AS1, which are hypomethylated and...

Full description

Bibliographic Details
Main Authors:	Juyeon Ham, Dawoon Jeong, Sungbin Park, Hyeon Woo Kim, Heejoo Kim, Sun Jung Kim
Format:	Article
Language:	English
Published:	Elsevier 2019-10-01
Series:	Journal of Ginseng Research
Online Access:	http://www.sciencedirect.com/science/article/pii/S1226845318303269

Similar Items

Improved anticancer effect of ginseng extract by microwave-assisted processing through the generation of ginsenosides Rg3, Rg5 and Rk1
by: Pilju Choi, et al.
Published: (2015-04-01)

Ginsenoside Rg1 from Panax ginseng enhances myoblast differentiation and myotube growth
by: Ga-Yeon Go, et al.
Published: (2017-10-01)

Anti-breast cancer activity of Fine Black ginseng (Panax ginseng Meyer) and ginsenoside Rg5
by: Shin-Jung Kim, et al.
Published: (2015-04-01)

Antihypertensive effect of Korean Red Ginseng by enrichment of ginsenoside Rg3 and arginine–fructose
by: Kyung Hee Lee, et al.
Published: (2016-07-01)

Ginsenosides Rg5 and Rk1, the skin-whitening agents in black ginseng
by: Yan Jin, et al.
Published: (2018-06-01)

Ginsenoside Rg3-enriched red ginseng extract inhibits platelet activation and in vivo thrombus formation
by: Dahye Jeong, et al.
Published: (2017-10-01)

ZNRD1 and Its Antisense Long Noncoding RNA ZNRD1-AS1 Are Oppositely Regulated by Cold Atmospheric Plasma in Breast Cancer Cells
by: Hyeon Woo Kim, et al.
Published: (2020-01-01)

Ginsenoside Rg3 Prevents Oncogenic Long Noncoding RNA ATXN8OS from Inhibiting Tumor-Suppressive microRNA-424-5p in Breast Cancer Cells
by: Heejoo Kim, et al.
Published: (2021-01-01)

Molecular signaling of ginsenosides Rb1, Rg1, and Rg3 and their mode of actions
by: Padmanaban Mohanan, et al.
Published: (2018-04-01)

Stereospecific anticancer effects of ginsenoside Rg3 epimers isolated from heat-processed American ginseng on human gastric cancer cell
by: Eun-Hwa Park, et al.
Published: (2014-01-01)

The effect of the ginsenoside RG-1 of Panax ginseng on mitosis in human blood leukocytes in vitro.
Published: (1979)

Alleviation of diabetic complications by ginsenoside Rg3-enriched red ginseng extract in western diet-fed LDL–/– mice
by: Evelyn Saba, et al.
Published: (2018-07-01)

Panax ginseng modulates cytokines in bone marrow toxicity and myelopoiesis: ginsenoside Rg1 partially supports myelopoiesis.
by: Hanumantha Rao Balaji Raghavendran, et al.
Published: (2012-01-01)

Effect of ginseng, ginsenoside Rg1 and prednisolone on aristolochic acid induced nephropathy in inbred mice
by: Yu-Fan Cheng, et al.
Published: (2008)

Effects of ginseng , ginsenoside Rg1 and N-acetylcysteine on cisplatin-induced nephrotoxicity in inbred mice
by: Zhi-Yun Huang, et al.
Published: (2008)

Ginseng pharmacology : signaling pathways of ginsenoside-Rg1 in human umbilical vein endothelial cells
by: Leung, Kar Wah
Published: (2006)

Relationship Between Ginsenoside Rg3 and Metabolic Syndrome
by: Hyunji Lee, et al.
Published: (2020-02-01)

Morphine dependence is attenuated by red ginseng extract and ginsenosides Rh2, Rg3, and compound K
by: Taddesse Yayeh, et al.
Published: (2016-10-01)

Korean Red Ginseng extract and ginsenoside Rg3 have anti-pruritic effects on chloroquine-induced itch by inhibition of MrgprA3/TRPA1-mediated pathway
by: Wook-Joo Lee, et al.
Published: (2018-10-01)

Beneficial effects of fermented black ginseng and its ginsenoside 20(S)-Rg3 against cisplatin-induced nephrotoxicity in LLC-PK1 cells
by: Myoung-Sik Han, et al.
Published: (2016-04-01)

Evaluation of glucosidases of Aspergillus niger strain comparing with other glucosidases in transformation of ginsenoside Rb1 to ginsenosides Rg3
by: Kyung Hoon Chang, et al.
Published: (2014-01-01)

Ginsenoside Rg3 Induces Browning of 3T3-L1 Adipocytes by Activating AMPK Signaling
by: Kyungtae Kim, et al.
Published: (2020-02-01)

Ginsenosides Rg1 from Panax ginseng: A Potential Therapy for Acute Liver Failure Patients?
by: Jinqiu Zhao, et al.
Published: (2014-01-01)

Ginsenoside Rg12, a new dammarane-type triterpene saponin from Panax ginseng root
by: Dong Gu Lee, et al.
Published: (2017-10-01)

Kinetic study for the optimization of ginsenoside Rg3 production by heat treatment of ginsenoside Rb1
by: Hoang Tung Vo, et al.
Published: (2015-10-01)

Microbial transformation of ginsenoside Rb1, Re and Rg1 and its contribution to the improved anti-inflammatory activity of ginseng
by: Shanshan Yu, et al.
Published: (2017-03-01)

Anti-Angiogenic Properties of Ginsenoside Rg3
by: Maryam Nakhjavani, et al.
Published: (2020-10-01)

Effects of gut microbiota on the pharmacokinetics of protopanaxadiol ginsenosides Rd, Rg3, F2, and compound K in healthy volunteers treated orally with red ginseng
by: Jeon-Kyung Kim, et al.
Published: (2020-07-01)

An improved method for the preparation of Ginsenoside Rg5 from ginseng fibrous root powder
by: Dan-dan Guo, et al.
Published: (2019-10-01)

Enrichment of the less polar ginsenoside (Rg3) from ginseng grown in New Zealand by post-harvest processing and extraction
by: Wei Chen, et al.
Published: (2021-07-01)

Study on Separation of Ginsenoside Rg1 and Ginsenoside Rb1 from Panax Notoginseng.
by: HO,TA-CHIH, et al.
Published: (2017)

Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy
by: Wu Chen, et al.
Published: (2020-02-01)

Effect of ginseng and ginsenosides on melanogenesis and their mechanism of action
by: Kwangmi Kim
Published: (2015-01-01)

Ginsenoside Rg1 augments oxidative metabolism and anabolic response of skeletal muscle in mice
by: Hyeon-Ju Jeong, et al.
Published: (2019-07-01)

Ginsenoside Rg3 Promotes Cell Growth Through Activation of mTORC1
by: Wei Liu, et al.
Published: (2021-09-01)

A Synergistic Anti-Diabetic Effect by Ginsenosides Rb1 and Rg3 through Adipogenic and Insulin Signaling Pathways in 3T3-L1 Cells
by: Hee-Do Hong, et al.
Published: (2021-02-01)

Korean Red Ginseng and Ginsenoside Rg3 Suppress Asian Sand Dust-Induced Epithelial–Mesenchymal Transition in Nasal Epithelial Cells
by: Chae, M.-H, et al.
Published: (2022)

Pharmacokinetic Comparison of 20(R)- and 20(S)-Ginsenoside Rh1 and 20(R)- and 20(S)-Ginsenoside Rg3 in Rat Plasma following Oral Administration of Radix Ginseng Rubra and Sheng-Mai-San Extracts
by: Xiaomei Fan, et al.
Published: (2017-01-01)

Ginsenoside Rg3 inhibits the biological activity of SGC‐7901
by: Qing Yang, et al.
Published: (2020-08-01)

Modification of ginsenoside composition in red ginseng (Panax ginseng) by ultrasonication
by: Sung-hyun Yoon, et al.
Published: (2016-07-01)