Structure Confirmation and Evaluation of a Nonsteroidal Inhibitor of 17β-Hydroxysteroid Dehydrogenase Type 10

Structure Confirmation and Evaluation of a Nonsteroidal Inhibitor of 17β-Hydroxysteroid Dehydrogenase Type 10

17β-Hydroxysteroid dehydrogenase type 10 (17β-HSD10) is a steroidogenesis enzyme known for its potential role in Alzheimer’s disease. For comparison purposes between steroidal and nonsteroidal 17β-HSD10 inhibitors 1 and 2, respectively, we attempted the chemical...

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Bibliographic Details
Main Authors: Sophie Boutin, Donald Poirier
Format: Article
Language:English
Published: MDPI AG 2018-07-01
Series:Magnetochemistry
Subjects:
NMR
chemical synthesis
enzyme inhibitor
17β-HSD10
Alzheimer’s
Online Access:http://www.mdpi.com/2312-7481/4/3/32

Internet

http://www.mdpi.com/2312-7481/4/3/32

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