Establishing the Clinical Utility of ctDNA Analysis for Diagnosis, Prognosis, and Treatment Monitoring of Retinoblastoma: The Aqueous Humor Liquid Biopsy

Establishing the Clinical Utility of ctDNA Analysis for Diagnosis, Prognosis, and Treatment Monitoring of Retinoblastoma: The Aqueous Humor Liquid Biopsy

Because direct tumor biopsy is prohibited for retinoblastoma (RB), eye-specific molecular biomarkers are not used in clinical practice for RB. Recently, we demonstrated that the aqueous humor (AH) is a rich liquid biopsy source of cell-free tumor DNA. Herein, we detail clinically-relevant molecular...

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Bibliographic Details
Main Authors: Liya Xu, Mary E. Kim, Ashley Polski, Rishvanth K. Prabakar, Lishuang Shen, Chen-Ching Peng, Mark W. Reid, Patricia Chévez-Barrios, Jonathan W. Kim, Rachana Shah, Rima Jubran, Peter Kuhn, David Cobrinik, Jaclyn A. Biegel, Xiaowu Gai, James Hicks, Jesse L. Berry
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cancers
Subjects:
retinoblastoma
aqueous humor
liquid biopsy
ctDNA
SCNA
precision oncology
Online Access:https://www.mdpi.com/2072-6694/13/6/1282

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https://www.mdpi.com/2072-6694/13/6/1282

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