Targeted Imaging of Tumor-Associated Macrophages by Cyanine 7-Labeled Mannose in Xenograft Tumors

Mannose receptor is considered as a hallmark of M2-oriented tumor-associated macrophages (TAMs), but its utility in TAMs was rarely reported. Therefore, deoxymannose (DM), a high-affinity ligand of mannose receptor, was labeled with near-infrared dye cyanine 7 (Cy7), and its feasibility of targeted...

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Bibliographic Details
Main Authors: Chong Jiang MD, Huawei Cai PhD, Xiaodong Peng MD, Ping Zhang PhD, Xiaoai Wu PhD, Rong Tian MD
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2017-01-01
Series:Molecular Imaging
Online Access:https://doi.org/10.1177/1536012116689499