Integrative approaches generate insights into the architecture of non-syndromic cleft lip with or without cleft palate

Integrative approaches generate insights into the architecture of non-syndromic cleft lip with or without cleft palate

Summary: Non-syndromic cleft lip with or without cleft palate (nsCL/P) is a common congenital facial malformation with a multifactorial etiology. Genome-wide association studies (GWASs) have identified multiple genetic risk loci. However, functional interpretation of these loci is hampered by the un...

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Bibliographic Details
Main Authors: Julia Welzenbach, Nigel L. Hammond, Miloš Nikolić, Frederic Thieme, Nina Ishorst, Elizabeth J. Leslie, Seth M. Weinberg, Terri H. Beaty, Mary L. Marazita, Elisabeth Mangold, Michael Knapp, Justin Cotney, Alvaro Rada-Iglesias, Michael J. Dixon, Kerstin U. Ludwig
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:HGG Advances
Subjects:
cleft
GWAS
regulatory effects
chromatin mark
craniofacial development
Online Access:http://www.sciencedirect.com/science/article/pii/S2666247721000191

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http://www.sciencedirect.com/science/article/pii/S2666247721000191

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