Case Report: ANXA2 Associated Life-Threatening Coagulopathy With Hyperfibrinolysis in a Patient With Non-APL Acute Myeloid Leukemia

Case Report: ANXA2 Associated Life-Threatening Coagulopathy With Hyperfibrinolysis in a Patient With Non-APL Acute Myeloid Leukemia

Patients with acute promyelocytic leukemia (APL) often present with potentially life-threatening hemorrhagic diathesis. The underlying pathomechanisms of APL-associated coagulopathy are complex. However, two pathways considered to be APL-specific had been identified: 1) annexin A2 (ANXA2)-associated...

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Bibliographic Details
Main Authors: Leo Ruhnke, Friedrich Stölzel, Lisa Wagenführ, Heidi Altmann, Uwe Platzbecker, Sylvia Herold, Andreas Rump, Evelin Schröck, Martin Bornhäuser, Johannes Schetelig, Malte von Bonin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
acute promyelocytic leukemia
acute myeloid leukemia
hyperfibrinolysis
disseminated intravascular coagulation
coagulopathy
ANXA2
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.666014/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.666014/full

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