Interleukin-15 plays a central role in human kidney physiology and cancer through the γc signaling pathway.

Interleukin-15 plays a central role in human kidney physiology and cancer through the γc signaling pathway.

The ability of Interleukin-15 (IL-15) to activate many immune antitumor mechanisms renders the cytokine a good candidate for the therapy of solid tumors, particularly renal cell carcinoma. Although IL-15 is being currently used in clinical trials, the function of the cytokine on kidney's compon...

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Bibliographic Details
Main Authors: Julien Giron-Michel, Sandy Azzi, Krystel Khawam, Erwan Mortier, Anne Caignard, Aurore Devocelle, Silvano Ferrini, Michela Croce, Hélène François, Lola Lecru, Bernard Charpentier, Salem Chouaib, Bruno Azzarone, Pierre Eid
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3283658?pdf=render

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http://europepmc.org/articles/PMC3283658?pdf=render

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