Development of Nanobodies Against Hemorrhagic and Myotoxic Components of Bothrops atrox Snake Venom

Snake envenoming is a globally neglected public health problem. Antivenoms produced using animal hyperimmune plasma remain the standard therapy for snakebites. Although effective against systemic effects, conventional antivenoms have limited efficacy against local tissue damage. In addition, potenti...

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Main Authors: Henri Bailon Calderon, Verónica Olga Yaniro Coronel, Omar Alberto Cáceres Rey, Elizabeth Gaby Colque Alave, Walter Jhon Leiva Duran, Carlos Padilla Rojas, Harrison Montejo Arevalo, David García Neyra, Marco Galarza Pérez, César Bonilla, Benigno Tintaya, Giulia Ricciardi, Natalia Smiejkowska, Ema Romão, Cécile Vincke, Juan Lévano, Mary Celys, Bruno Lomonte, Serge Muyldermans
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00655/full