In vivo monitoring of the therapeutic efficacy of a CXCR1/2 inhibitor with 18F-FDG PET/CT imaging in experimental head and neck carcinoma: A feasibility study

In vivo monitoring of the therapeutic efficacy of a CXCR1/2 inhibitor with 18F-FDG PET/CT imaging in experimental head and neck carcinoma: A feasibility study

The chemokine receptors CXCR1/2 play a key role in the aggressiveness of several types of cancers including head and neck squamous cell carcinomas (HNSCCs). In HNSCCs, CXCR1/2 signaling promotes cell proliferation and angiogenesis leading to tumor growth and metastasis. The competitive inhibitor of...

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Bibliographic Details
Main Authors: Christopher Montemagno, Benjamin Serrano, Jérôme Durivault, Valérie Nataf, François Mocquot, Régis Amblard, Valérie Vial, Cyril Ronco, Rachid Benhida, Maeva Dufies, Marc Faraggi, Gilles Pagès
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
CXCR1/2
HNSCCs
Chemical inhibitor
18F-FDG
PET/CT imaging
Online Access:http://www.sciencedirect.com/science/article/pii/S240558082100193X

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http://www.sciencedirect.com/science/article/pii/S240558082100193X

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