Aronia melanocarpa Leaves as a Source of Chlorogenic Acids, Anthocyanins, and Sorbitol, and Their Anti-Inflammatory Activity

Aronia melanocarpa E. berries are a valuable component of the healthy diet. They are extremely high in phenolics exhibiting strong antioxidant properties. However, not much information is available on the chemical composition and bioactive potential of chokeberry leaves. Therefore, the analyses of...

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Main Authors: Agnieszka Zielińska, Dorota Bryk, Katarzyna Paradowska, Iwona Wawer
Format: Article
Language:English
Published: Institute of Animal Reproduction and Food Research 2020-12-01
Series:Polish Journal of Food and Nutrition Sciences
Subjects:
nmr
Online Access:http://www.journalssystem.com/pjfns/Aronia-melanocarpa-leaves-as-a-source-of-chlorogenic-acids-anthocyanins-and-sorbitol,130255,0,2.html
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spelling doaj-0e05b00a21224f2cbbab0087364a6e182020-12-21T08:12:42ZengInstitute of Animal Reproduction and Food ResearchPolish Journal of Food and Nutrition Sciences2083-60072020-12-0170440941810.31883/pjfns/130255130255Aronia melanocarpa Leaves as a Source of Chlorogenic Acids, Anthocyanins, and Sorbitol, and Their Anti-Inflammatory ActivityAgnieszka Zielińska0Dorota Bryk1Katarzyna Paradowska2Iwona Wawer3Department of Physical Chemistry, Chair of Physical Pharmacy and Bioanalysis, Faculty of Pharmacy, Medical University of Warsaw, Banacha Str. 1, 02-097 Warsaw, PolandChair of Biochemistry and Clinical Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Banacha Str. 1, 02-097 Warsaw, PolandDepartment of Physical Chemistry, Chair of Physical Pharmacy and Bioanalysis, Faculty of Pharmacy, Medical University of Warsaw, Banacha Str. 1, 02-097 Warsaw, PolandHerbology Department, Carpathian State University, Rynek 1, 38-400 Krosno, PolandAronia melanocarpa E. berries are a valuable component of the healthy diet. They are extremely high in phenolics exhibiting strong antioxidant properties. However, not much information is available on the chemical composition and bioactive potential of chokeberry leaves. Therefore, the analyses of sugars and phenolics of extracts from chokeberry leaves collected from June to October were performed using spectroscopic (NMR) and chromatographic (HPLC-DAD/RI, GC-MS) methods. The leaf extracts contained a significant amount of sorbitol, especially those made of leaves collected since June to July (avg. 145.2 mg/g d.w.). The average contents of Cya-3-Gal and chlorogenic acids in the extracts were at 0.52 mg g d.w. and up to 13.1 mg/g d.w., respectively. Chokeberry leaf extracts from green and red leaves were subjected to the in vitro study on human umbilical vein endothelial cells (HUVCs). Both extracts suppressed TNF-α-induced surface expression of ICAM-1 and VCAM-1 molecules, and exhibited anti-adhesive and anti-inflammatory properties. Green and red leaves may foster a therapeutic potential in the prevention of atherosclerosis and other pathological events involving leucocyte adhesion. That is why chokeberry leaves can be considered as a promising component of functional foods owing to the high content of chlorogenic acids and sorbitol.http://www.journalssystem.com/pjfns/Aronia-melanocarpa-leaves-as-a-source-of-chlorogenic-acids-anthocyanins-and-sorbitol,130255,0,2.htmlaronia melanocarpa leavessorbitolchlorogenic acidsanti-inflammatory activitynmrhplc
collection DOAJ
language English
format Article
sources DOAJ
author Agnieszka Zielińska
Dorota Bryk
Katarzyna Paradowska
Iwona Wawer
spellingShingle Agnieszka Zielińska
Dorota Bryk
Katarzyna Paradowska
Iwona Wawer
Aronia melanocarpa Leaves as a Source of Chlorogenic Acids, Anthocyanins, and Sorbitol, and Their Anti-Inflammatory Activity
Polish Journal of Food and Nutrition Sciences
aronia melanocarpa leaves
sorbitol
chlorogenic acids
anti-inflammatory activity
nmr
hplc
author_facet Agnieszka Zielińska
Dorota Bryk
Katarzyna Paradowska
Iwona Wawer
author_sort Agnieszka Zielińska
title Aronia melanocarpa Leaves as a Source of Chlorogenic Acids, Anthocyanins, and Sorbitol, and Their Anti-Inflammatory Activity
title_short Aronia melanocarpa Leaves as a Source of Chlorogenic Acids, Anthocyanins, and Sorbitol, and Their Anti-Inflammatory Activity
title_full Aronia melanocarpa Leaves as a Source of Chlorogenic Acids, Anthocyanins, and Sorbitol, and Their Anti-Inflammatory Activity
title_fullStr Aronia melanocarpa Leaves as a Source of Chlorogenic Acids, Anthocyanins, and Sorbitol, and Their Anti-Inflammatory Activity
title_full_unstemmed Aronia melanocarpa Leaves as a Source of Chlorogenic Acids, Anthocyanins, and Sorbitol, and Their Anti-Inflammatory Activity
title_sort aronia melanocarpa leaves as a source of chlorogenic acids, anthocyanins, and sorbitol, and their anti-inflammatory activity
publisher Institute of Animal Reproduction and Food Research
series Polish Journal of Food and Nutrition Sciences
issn 2083-6007
publishDate 2020-12-01
description Aronia melanocarpa E. berries are a valuable component of the healthy diet. They are extremely high in phenolics exhibiting strong antioxidant properties. However, not much information is available on the chemical composition and bioactive potential of chokeberry leaves. Therefore, the analyses of sugars and phenolics of extracts from chokeberry leaves collected from June to October were performed using spectroscopic (NMR) and chromatographic (HPLC-DAD/RI, GC-MS) methods. The leaf extracts contained a significant amount of sorbitol, especially those made of leaves collected since June to July (avg. 145.2 mg/g d.w.). The average contents of Cya-3-Gal and chlorogenic acids in the extracts were at 0.52 mg g d.w. and up to 13.1 mg/g d.w., respectively. Chokeberry leaf extracts from green and red leaves were subjected to the in vitro study on human umbilical vein endothelial cells (HUVCs). Both extracts suppressed TNF-α-induced surface expression of ICAM-1 and VCAM-1 molecules, and exhibited anti-adhesive and anti-inflammatory properties. Green and red leaves may foster a therapeutic potential in the prevention of atherosclerosis and other pathological events involving leucocyte adhesion. That is why chokeberry leaves can be considered as a promising component of functional foods owing to the high content of chlorogenic acids and sorbitol.
topic aronia melanocarpa leaves
sorbitol
chlorogenic acids
anti-inflammatory activity
nmr
hplc
url http://www.journalssystem.com/pjfns/Aronia-melanocarpa-leaves-as-a-source-of-chlorogenic-acids-anthocyanins-and-sorbitol,130255,0,2.html
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