Implication of Posttranslational Histone Modifications in Nucleotide Excision Repair

Implication of Posttranslational Histone Modifications in Nucleotide Excision Repair

Histones are highly alkaline proteins that package and order the DNA into chromatin in eukaryotic cells. Nucleotide excision repair (NER) is a conserved multistep reaction that removes a wide range of generally bulky and/or helix-distorting DNA lesions. Although the core biochemical mechanism of NER...

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Bibliographic Details
Main Author: Shisheng Li
Format: Article
Language:English
Published: MDPI AG 2012-09-01
Series:International Journal of Molecular Sciences
Subjects:
nucleotide excision repair
global genomic repair
histone modifications
acetylation
methylation
phosphorylation
ubiquitination
Online Access:http://www.mdpi.com/1422-0067/13/10/12461

Internet

http://www.mdpi.com/1422-0067/13/10/12461

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