Modeling Long-Term Graft Survival With Time-Varying Covariate Effects: An Application to a Single Kidney Transplant Centre in Johannesburg, South Africa

Modeling Long-Term Graft Survival With Time-Varying Covariate Effects: An Application to a Single Kidney Transplant Centre in Johannesburg, South Africa

Objectives: Patients' characteristics that could influence graft survival may also exhibit non-constant effects over time; therefore, violating the important assumption of the Cox proportional hazard (PH) model. We describe the effects of covariates on the hazard of graft failure in the presenc...

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Bibliographic Details
Main Authors: Okechinyere J. Achilonu, June Fabian, Eustasius Musenge
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Public Health
Subjects:
graft survival
time varying covariate effect
Cox PH model
purposeful selection
additive hazard models
Online Access:https://www.frontiersin.org/article/10.3389/fpubh.2019.00201/full

Internet

https://www.frontiersin.org/article/10.3389/fpubh.2019.00201/full

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