Maladaptive synaptic plasticity in L-DOPA-induced dyskinesia

The emergence of L-DOPA-induced dyskinesia (LID) in patients with Parkinson disease (PD) could be due to maladaptive plasticity of corticostriatal synapses in response to L-DOPA treatment. A series of recent studies has revealed that LID is associated with marked morphological plasticity of striatal...

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Bibliographic Details
Main Authors: Qiang Wang, Wangming Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-12-01
Series:Frontiers in Neural Circuits
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2016.00105/full