Inclusion complex of tamibarotene with hydroxypropyl-β-cyclodextrin: Preparation, characterization, in-vitro and in-vivo evaluation

The goal of this study was to improve the solubility and oral bioavailability of tamibarotene by complexing it with hydroxypropyl-β-cyclodextrin (HP-β-CD). The inclusion complex of tamibarotene with hydroxypropyl-β-cyclodextrin (Am80-HP-β-CD) was prepared through a freeze-drying method at the mole r...

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Bibliographic Details
Main Authors: Ying Yang, Jinhua Gao, Xiaoyu Ma, Guihua Huang
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:Asian Journal of Pharmaceutical Sciences
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1818087616300885