Polysaccharides As Viscosupplementation Agents: Structural Molecular Characteristics but Not Rheology Appear Crucial to the Therapeutic Response

IntroductionMost clinical studies and basic research document viscosupplementation (VS) in terms of effectiveness and safety, but only a few highlight its molecular mechanisms of action. Besides, there is generally focus on hyaluronic acid (HA) as being the most relevant polysaccharide to reach the...

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Bibliographic Details
Main Authors: Rita C. Machado, Susana Capela, Francisco A. C. Rocha
Format: Article
Published: Frontiers Media S.A. 2017-06-01
Series:Frontiers in Medicine
Online Access:http://journal.frontiersin.org/article/10.3389/fmed.2017.00082/full