Interferon Consensus Sequence-Binding Protein 8, a Tumor Suppressor, Suppresses Tumor Growth and Invasion of Non-Small Cell Lung Cancer by Interacting with the Wnt/β-Catenin Pathway

Interferon Consensus Sequence-Binding Protein 8, a Tumor Suppressor, Suppresses Tumor Growth and Invasion of Non-Small Cell Lung Cancer by Interacting with the Wnt/β-Catenin Pathway

Background/Aims: Interferon consensus sequence-binding protein 8 (IRF8) belongs to a family of interferon (IFN) regulatory factors that modulates various important physiological processes including carcinogenesis. As reported by others and our group, IRF8 expression is silenced by DNA methylation in...

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Bibliographic Details
Main Authors: Lin Ye, Tingxiu Xiang, Jing Zhu, Dairong Li, Qin Shao, Weiyan Peng, Jun Tang, Lili Li, Guosheng Ren
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
IRF8
NSCLC
Tumor suppressor
CpG methylation
TCF/LEF
Wnt/β-catenin
Online Access:https://www.karger.com/Article/FullText/495399

Internet

https://www.karger.com/Article/FullText/495399

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