Epigenetic clocks for gestational age: statistical and study design considerations

Abstract In this letter to the editor, we highlight some concerns with a recently published method to estimate gestational age at delivery from DNA methylation data. We conduct novel analyses to highlight the implications of different choices in study design and statistical methods for the predictio...

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Bibliographic Details
Main Authors: Andrew J. Simpkin, Matthew Suderman, Laura D. Howe
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Clinical Epigenetics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13148-017-0402-y