Increase of circulating IGFBP-4 following genotoxic stress and its implication for senescence
Senescent cells secrete several molecules, collectively named senescence-associated secretory phenotype (SASP). In the SASP of cells that became senescent following several in vitro chemical and physical stress, we identified the IGFBP-4 protein that can be considered a general stress mediator. This...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-03-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/54523 |