Efficient Microwave Assisted Syntheses of 2,5-Diketopiperazines in Aqueous Media
Aqueous in situ one-pot N-Boc-deprotection-cyclization of Nα-Boc-dipeptidyl-tert-butyl and methyl esters under microwave irradiation afforded 2,5-diketopiperazines (DKPs) in excellent yields. This protocol is rapid, safe, environmentally friendly, and highly efficient, and showed that the tert-butox...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2009-07-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/14/8/2836/ |