Nonclinical Development of BCG Replacement Vaccine Candidates

Nonclinical Development of BCG Replacement Vaccine Candidates

The failure of current Mycobacterium bovis bacille Calmette–Guérin (BCG) vaccines, given to neonates to protect against adult tuberculosis and the risk of using these live vaccines in HIV-infected infants, has emphasized the need for generating new, more efficacious and safer replacement vaccines. W...

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Bibliographic Details
Main Authors: Bernd Eisele, Martin Gengenbacher, Reginald Kidd, David McCown, Sheldon Morris, Steven Derrick, David Hokey, Dominick Laddy, Rosemary Chang, Megan Fitzpatrick, Leander Grode, Kamalakannan Velmurugan, Stefan H.E. Kaufmann, John Fulkerson, Michael J. Brennan
Format: Article
Language:English
Published: MDPI AG 2013-04-01
Series:Vaccines
Subjects:
tuberculosis
live vaccines
Mycobacterium tuberculosis
recombinant BCG
Online Access:http://www.mdpi.com/2076-393X/1/2/120

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