DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION

DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION

Some steps were taken to elaborate a method for the preparation of polymeric microspheres using flow microreactors by emulsifying the solution of methacrylic acid esters copolymer in an aqueous PVA solution followed by extraction and evaporation of the solvent. The effect of process parameters on th...

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Main Authors: S. A. Kedik, E. A. Petrova, E. S. Zhavoronok, A. V. Panov, V. V. Suslov
Format: Article
Language:Russian
Published: MIREA - Russian Technological University 2013-08-01
Series:Тонкие химические технологии
Subjects:
polymeric microspheres, diagnostic test systems, flow microreactors, latex agglutination.
Online Access:https://www.finechem-mirea.ru/jour/article/view/564
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spelling doaj-0fc096d7916348339c68decda9cdc2862021-07-28T13:23:57ZrusMIREA - Russian Technological UniversityТонкие химические технологии2410-65932686-75752013-08-01841117558DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTIONS. A. Kedik0E. A. Petrova1E. S. Zhavoronok2A. V. Panov3V. V. Suslov4M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571Some steps were taken to elaborate a method for the preparation of polymeric microspheres using flow microreactors by emulsifying the solution of methacrylic acid esters copolymer in an aqueous PVA solution followed by extraction and evaporation of the solvent. The effect of process parameters on the characteristics of polymeric microspheres with a predetermined set of properties (mean size, polydispersity) potentially suitable for use as carriers in bioligands for diagnostic test systems was investigated. The dependence of the average particle size on the microreactor type, concentration of copolymer solution in methylene chloride and polyvinyl alcohol in water and the ratio of flow rates of organic and aqueous phases was stated, and the optimal process conditions were selected.https://www.finechem-mirea.ru/jour/article/view/564polymeric microspheres, diagnostic test systems, flow microreactors, latex agglutination.
collection DOAJ
language Russian
format Article
sources DOAJ
author S. A. Kedik
E. A. Petrova
E. S. Zhavoronok
A. V. Panov
V. V. Suslov
spellingShingle S. A. Kedik
E. A. Petrova
E. S. Zhavoronok
A. V. Panov
V. V. Suslov
DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION
Тонкие химические технологии
polymeric microspheres, diagnostic test systems, flow microreactors, latex agglutination.
author_facet S. A. Kedik
E. A. Petrova
E. S. Zhavoronok
A. V. Panov
V. V. Suslov
author_sort S. A. Kedik
title DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION
title_short DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION
title_full DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION
title_fullStr DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION
title_full_unstemmed DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION
title_sort development of microreactor method for polymeric microspheres production used in test systems based on latex agglutination reaction
publisher MIREA - Russian Technological University
series Тонкие химические технологии
issn 2410-6593
2686-7575
publishDate 2013-08-01
description Some steps were taken to elaborate a method for the preparation of polymeric microspheres using flow microreactors by emulsifying the solution of methacrylic acid esters copolymer in an aqueous PVA solution followed by extraction and evaporation of the solvent. The effect of process parameters on the characteristics of polymeric microspheres with a predetermined set of properties (mean size, polydispersity) potentially suitable for use as carriers in bioligands for diagnostic test systems was investigated. The dependence of the average particle size on the microreactor type, concentration of copolymer solution in methylene chloride and polyvinyl alcohol in water and the ratio of flow rates of organic and aqueous phases was stated, and the optimal process conditions were selected.
topic polymeric microspheres, diagnostic test systems, flow microreactors, latex agglutination.
url https://www.finechem-mirea.ru/jour/article/view/564
work_keys_str_mv AT sakedik developmentofmicroreactormethodforpolymericmicrospheresproductionusedintestsystemsbasedonlatexagglutinationreaction
AT eapetrova developmentofmicroreactormethodforpolymericmicrospheresproductionusedintestsystemsbasedonlatexagglutinationreaction
AT eszhavoronok developmentofmicroreactormethodforpolymericmicrospheresproductionusedintestsystemsbasedonlatexagglutinationreaction
AT avpanov developmentofmicroreactormethodforpolymericmicrospheresproductionusedintestsystemsbasedonlatexagglutinationreaction
AT vvsuslov developmentofmicroreactormethodforpolymericmicrospheresproductionusedintestsystemsbasedonlatexagglutinationreaction
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