Latency-Associated Expression of Human Cytomegalovirus US28 Attenuates Cell Signaling Pathways To Maintain Latent Infection

Reactivation of human cytomegalovirus (HCMV) latent infection from early myeloid lineage cells constitutes a threat to immunocompromised or immune-suppressed individuals. Consequently, understanding the control of latency and reactivation to allow targeting and killing of latently infected cells cou...

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Bibliographic Details
Main Authors: Benjamin A. Krishna, Emma L. Poole, Sarah E. Jackson, Martine J. Smit, Mark R. Wills, John H. Sinclair, Michael J. Imperiale
Format: Article
Language:English
Published: American Society for Microbiology 2017-12-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/6/e01754-17