Immune modulation by complement receptor 3-dependent human monocyte TGF-β1-transporting vesicles

Immune modulation by complement receptor 3-dependent human monocyte TGF-β1-transporting vesicles

Extracellular vesicles can carry immunoregulatory cytokines such as TGF-β. Here the authors use CD11b-deficient mice and macrophages to show that such vesicles carrying TGF-β are produced in response to Candida albicans infections and can limit the proinflammatory response partly via a positive feed...

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Bibliographic Details
Main Authors: Luke D. Halder, Emeraldo A. H. Jo, Mohammad Z. Hasan, Marta Ferreira-Gomes, Thomas Krüger, Martin Westermann, Diana I. Palme, Günter Rambach, Niklas Beyersdorf, Cornelia Speth, Ilse D. Jacobsen, Olaf Kniemeyer, Berit Jungnickel, Peter F. Zipfel, Christine Skerka
Format: Article
Language:English
Published: Nature Publishing Group 2020-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-16241-5

Internet

https://doi.org/10.1038/s41467-020-16241-5

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