KiRNet: Kinase-centered network propagation of pharmacological screen results

KiRNet: Kinase-centered network propagation of pharmacological screen results

Summary: The ever-increasing size and scale of biological information have popularized network-based approaches as a means to interpret these data. We develop a network propagation method that integrates kinase-inhibitor-focused functional screens with known protein-protein interactions (PPIs). This...

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Bibliographic Details
Main Authors: Thomas Bello, Marina Chan, Martin Golkowski, Andrew G. Xue, Nithisha Khasnavis, Michele Ceribelli, Shao-En Ong, Craig J. Thomas, Taranjit S. Gujral
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Cell Reports: Methods
Subjects:
kinase
network
propagation
computational
modeling
protein
Online Access:http://www.sciencedirect.com/science/article/pii/S2667237521000072

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http://www.sciencedirect.com/science/article/pii/S2667237521000072

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