CAMKK2-CAMK4 signaling regulates transferrin trafficking, turnover, and iron homeostasis
Abstract Background Circulatory iron is a hazardous biometal. Therefore, iron is transported in a redox-safe state by a serum glycoprotein - transferrin (TF). Different organs acquire iron from the systemic circulation through a tightly regulated mechanism at the blood-tissue interface which involve...
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| Format: | Article |
| Language: | English |
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BMC
2020-05-01
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| Series: | Cell Communication and Signaling |
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| Online Access: | http://link.springer.com/article/10.1186/s12964-020-00575-0 |