Induced prion protein controls immune-activated retroviruses in the mouse spleen.

Induced prion protein controls immune-activated retroviruses in the mouse spleen.

The prion protein (PrP) is crucially involved in transmissible spongiform encephalopathies (TSE), but neither its exact role in disease nor its physiological function are known. Here we show for mice, using histological, immunochemical and PCR-based methods, that stimulation of innate resistance was...

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Bibliographic Details
Main Authors: Marius Lötscher, Mike Recher, Karl S Lang, Alexander Navarini, Lukas Hunziker, Roger Santimaria, Markus Glatzel, Petra Schwarz, Jürg Böni, Rolf M Zinkernagel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2063463?pdf=render

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http://europepmc.org/articles/PMC2063463?pdf=render

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