Persistence and reversal of plasmid-mediated antibiotic resistance

It is unclear whether the transfer of plasmids carrying antibiotic resistance genes can explain their persistence when antibiotics are not present. Here, Lopatkin et al. show that conjugal plasmids, even when costly, are indeed transferred at sufficiently high rates to be maintained in the absence o...

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Bibliographic Details
Main Authors: Allison J. Lopatkin, Hannah R. Meredith, Jaydeep K. Srimani, Connor Pfeiffer, Rick Durrett, Lingchong You
Format: Article
Language:English
Published: Nature Publishing Group 2017-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-017-01532-1