Analysis of copy number variation in dogs implicates genomic structural variation in the development of anterior cruciate ligament rupture.

Analysis of copy number variation in dogs implicates genomic structural variation in the development of anterior cruciate ligament rupture.

Anterior cruciate ligament (ACL) rupture is an important condition of the human knee. Second ruptures are common and societal costs are substantial. Canine cranial cruciate ligament (CCL) rupture closely models the human disease. CCL rupture is common in the Labrador Retriever (5.79% prevalence), ~1...

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Bibliographic Details
Main Authors: Emily E Binversie, Lauren A Baker, Corinne D Engelman, Zhengling Hao, John J Moran, Alexander M Piazza, Susannah J Sample, Peter Muir
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2020-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0244075

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https://doi.org/10.1371/journal.pone.0244075

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