N-wasp is essential for the negative regulation of B cell receptor signaling.

N-wasp is essential for the negative regulation of B cell receptor signaling.

Negative regulation of receptor signaling is essential for controlling cell activation and differentiation. In B-lymphocytes, the down-regulation of B-cell antigen receptor (BCR) signaling is critical for suppressing the activation of self-reactive B cells; however, the mechanism underlying the nega...

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Bibliographic Details
Main Authors: Chaohong Liu, Xiaoming Bai, Junfeng Wu, Shruti Sharma, Arpita Upadhyaya, Carin I M Dahlberg, Lisa S Westerberg, Scott B Snapper, Xiaodong Zhao, Wenxia Song
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-11-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC3818172?pdf=render

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