MALAT1 modulates miR-146’s protection of microvascular endothelial cells against LPS-induced NF-κB activation and inflammatory injury

To investigate the role of miR-146 and its possible relationship with MALAT1 in LPS-induced inflammation in human microvascular endothelial cells (HMECs), HMEC-1 cells were treated with LPS to construct an inflammatory injury cell model, and the cell viability, TNF-α and IL-6 secretion and the expre...

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Bibliographic Details
Main Authors: Lin-Lin Feng, Wei-Na Xin, Xiu-Li Tian
Format: Article
Language:English
Published: SAGE Publishing 2019-10-01
Series:Innate Immunity
Online Access:https://doi.org/10.1177/1753425919861427